Saturday, June 26, 2010

The Engineering of...the contemporary within the historical

Was a bit under the weather this week, but had to do a presentation of my data to our PI and learn how to use a new microscopy system. The lab has been busy because we have a special visitor coming on Monday… Prince Albert of Monaco! How cool is that?! Think he will autograph my lab coat? Apparently he is giving away some cash and will be touring some of the bigger laboratories on the campus to see what we do.

World Cup hype is stronger than ever. Went to watch the Germany versus Ghana match on a big screen set up at the foot of the Eiffel Tower. Quite fittingly, the Tower lights started flickering at the conclusion. Has been nice walking all around the city- each arondissement feels a little different from the next.

French technology has not been treating me well this week. First, because my Internet connection is via the work network, they have been blocking a lot of websites. So, if you tried to contact me through Facebook, I haven't seen it! Please just email! Merci! French TV is also a bit strange. The frequency/frame rate is 50 Hz, but the human eye can detect frequencies as fast as about 65 Hz, so the screen looks like it is flickering!



The weekend has been fun so far…Went to the Centre Pompidou today, a fantastic modern art museum. It is filled with Picasso and Matisse and Kandinsky! My favorites had to be the kinetic art. The outside of the building is seven floors of steel and glass. Its bright pipes are color-coded according to their contents and an escalator climbs up the side. Had a cool exhibit about Coney Island's "Dreamland" and, my personal favorite, the Guerilla Girls! They dress up in gorilla costumes and go out to fight against gender discrimination in the art world (ex. Did you know… "Less than 5% of the artists in the Metropolitan Museum of Art are women, but 85% of the nudes are female"?)



This weekend we are breaking out of the country and heading to Brugges, Belgium: land of the Flemmish master painters. Woohoo! Can't wait to get me some chocolate!

A la prochaine-

Sunday, June 20, 2010

The Engineering of...getting my tourist on

Bon soir! Coming to you again from Paris with much to tell!

Now that more American interns are here, we have been trying to fit in lots of visits and activities every day. Started the week with a stroll along the entire length of the Champs Elysees one evening, including the oh-so-fabulous fashion district: a street lined with the likes of Chanel, Dior, Prada… They have guards that stand at attention outside the stores all night, also looking dapper!

Ended the week with a visit to the Pasteur Museum, right next to my laboratory building. Pasteur used to live there and almost all of the original furniture is still as it was in the 1800's. It is interesting that Pasteur actually didn't start as a biologist, but rather was requested by some important higher-ups to apply his chemistry knowledge to problems plaguing the animals/plants of the region. The museum even has three glass containers with fluid still sterile from the late 1800's when Pasteur made them! Also didn't know that Pasteur was such an amazing artist, great with pastel portraiture.

Poor Pasteur was kind of a sad dude, losing all but two of his children to disease and later suffering from paralyzing illness, himself. His crypt is located underneath the house; he is one of the only famous Frenchmen not to be buried in the Paris Pantheon. After the guide opens up this creaking iron gate, you enter this crazy room covered in glittering gold mosaic tiles depicting scenes important to Pasteur's work (the silkworms, rabid dogs, hens, grape vines...). In a morbid way, it was…gorgeous! The man himself lies there under the angels of Charity, Faith, Hope, and Science ("the mother, daughter, and sister of the other three"). And nearby is his wife, under the inscription: "dedicated supporter of Pasteur's work and life." Gee, thanks for the credit.

After the historical rendezvous, I left to more modern pursuits. Watched the UK versus Algeria World Cup soccer match at an "English" pub nearby the Parisian Pantheon. What a crowd!



This weekend was quite packed with sightseeing. Saturday was "Death Day." Started with the Catacombs. Such an interesting place...six million people's bones buried underground in these massive piles. Used to be an old mining quarry, so ceiling and walls were drippy stone. The bones weren't even stabilized-- we could pick up and touch them. Sign upon entering reads in French "Stop! This is the Empire of the Dead." Spooky! We went far underground and walked beneath the Parisian streets all around these niches filled with bones. Crazy that the last person put there was in 1920! (Mostly, though, in the mid 1800s after complaints of disease from the cemeteries above ground.)



Next, went to Pere Lachaise Cemetery. A wild old place with hundreds of mausoleums sitting above ground made of stone and iron. Most from the 1700s to the 1800s, but many later, too. Lots of famous people are buried there-- I saw Jim Morrison, Oscar Wilde, and Chopin's graves!



Then, off to the Hotel des Invalides. It is huge and filled with military history and artifacts from the ancient to the modern times, with a big focus on Medieval armory and WWI-II. Napoleon's tomb is there; his body was brought back from exile to be placed inside this huge (disproportionate to his size) sarcophagus, six layers thick! Surrounding, on the walls, are Grecian scenes all with Mr. Napoleon as the star! Very opulent place.

Ended the day with delicioso crepes, first with jambon and fromage and next with home-made toffee! A definite offset to the goriness of the day!



Today was only in the 50's, and after yesterday I thought "Church Day" would be a fitting follow-up, so I took the metro to Sainte-Chapelle. It was built in traditional High-Gothic style and is known for its fifteen massive stained glass windows—over 70% are original. The Chapel used to house very precious (pricey, for Louis IX) relics of Christ.



Next, I found the Crypte Archéologique du Parvis Notre-Dame. It encloses the excavation site of the foundations of Roman buildings located beneath Notre Dame square—an ancient city within an old city!

Planning more weekend trips and will be sure to update…Ciao ciao!

Tuesday, June 15, 2010

The Engineering of...getting personal

I heard something kind of cool today: Biomedical researchers may often view science from the third person-- it, them, he, she -- which makes it impersonal. We need to start thinking in the first person -- I, we -- so that we can better sense the impact of our work within the greater community of humanity that we are all a part of! Yes, even those cells you are poking may have feelings, too...

Why should the world care about our project? Well, we are creating a better tool to diagnose infection, especially bacterial. Typically, instruments that utilize light are hindered by the scattering and absorptive environment of the body. The techniques we are testing aim to actually use this environment to our advantage.

Attended another conference this morning aiming to further enhance the unity of the research community by creating a multi-user database for image acquisition, analysis, modification, and distribution called OME: Open Microscopy Environment. I found applications outside the realm of the petri dish and think I will encourage my future medical colleagues to use the database for storage of patients' medical images and sharing amongst specialists.

Sunday, June 13, 2010

The Engineering of...a masterpiece

The man himself...on canvas. A visit to the Musee d'Orsay today along the Seine brought me to the famous portrait of Louis Pasteur. The Musee focuses on artwork primarily from the late 1800s, but the building itself is quite gorgeous- built for the Universal Exhibition in the early 1900s in an old train station. During this period of artwork, artists were getting away from the "science" of art...there was more imagination, dream-like utopian images and creative techniques. Pastels became a popular medium (meant for the "delicate features in the portraiture of girls, not aged subjects"). The van Gogh, Cezanne, and Degas pieces totally stopped me in my tracks.

The science of artistic preservation is another challenging field. Pastels, especially, can be sprayed and stick better to a rougher texture. But, they sadly still flake away and age over time. Olay needs to get on that.

Learned how to navigate the metro yesterday and am now all about it. Super quick, reliable, and cheap. Also feeling the hype of the World Cup. Those tied finishes are just so unsatisfying... Ciao ciao!

Wednesday, June 9, 2010

The Engineering of...Doing Conferences Right

As I write, I am eating the best science experiment ever: the Parisian baguette. Je t'aime! Everyone picks one up after work; I get off so late it was down to the last one in the Patisserie, but I snatched that baby up, merci beaucoup.

Today I went to the international "Young Researchers in the Life Sciences" conference sponsored by my Institute and the Curie Institute. Met a couple other American attendees there and will be going to the "American lunch" on Friday. At 10 a.m. they had a wine and cheese break and tonight they have a rock band playing. Only the French!

Got some good bioluminescence images of cells today- just me and my black box. Spent part of the day designing experiments I'll do to fulfill the patent we just got.

Watching the French equivalent of American Idol ("Nouvelle Star"). They pretty much sing all American/English songs, but their accents are really distracting ("You got mee zo ay can't zleep aaht night!").

Drizzly today, but hit the pavement after work to check out the Rue LeCourbe. It is the longest straight, continuous stretch of road in France! Loving all of the little cars; can I take a Mini home with me please?

Monday, June 7, 2010

The Engineering of...living like the French.





Whew! What a whirlwind weekend!

Arrived in Paris Friday and took the metro into the city. Decided to walk off the jetlag by trekking to the Eiffel Tower and the Luxembourg Gardens.

Just worked a ten hour work day, despite the typical 35 hour/week schedule. Have some great mentors from England and France. Tuning my ear to the language is becoming easier. Love how they pronounce my name like "Shelsee Samso."

The lifestyle is truly more relaxed. The work day doesn't start until 9:30, lunch is over an hour long, and people (really) stop and smell the roses. Want to look like a French person? Walk slowly and carry a reusable shopping bag. The lab doesn't look like your typical lab- there are gardens surrounding the stone buildings and a museum dedicated to Louis Pasteur. Life is mostly outside, walking or biking from place to place, eating on the patios. The pigeons and dogs run the streets. My quarters are pretty tiny, including my Jetson's/airplane-style capsule bathroom, so I don't blame 'em for wanting some fresh air. Especially since it is light out until 10:30.

Learning lots of new techniques and how to use some cutting-edge bioluminescence equipment...and it's only the premier jour!

Thursday, June 3, 2010

The Engineering of...l'avion

It's D-Day! Bags are packed (teetering on the 23 kilogram limit). A "cornucopia," dare I say, of maps stowed away for this directionally-challenged traveler. Got my aisle seat reserved and got my jumpin' jacks out of the way in preparation for a long sit. Upon arrival, meeting a postdoc from my lab to take the train into Paris. Bon voyage!